Aging is a natural physiological process. A new study shows that the process continues, but not at a constant rate of development, which is often referred to as the feeling of \"getting older all of a sudden.\"
A new study published in the journal Nature Medicine recently showed that there are three gears for aging:34,60 and 78. Researchers at the Alzheimer's Research Center at Stanford University, who analyzed plasma data from 4,263 subjects aged 18 to 95, measured levels of about 3,000 different proteins and found that protein levels remained relatively stable overall, but the readings of multiple proteins changed significantly at the three ages. The researchers explain that these changes in protein levels are not only characteristic of human aging, but are more likely to be the cause of it. \"As research progresses, we hope to pass blood tests to measure how old people are at the molecular level.\" Professor Tony Weiss-Core, who led the study, said:\" The more we know about age, the more we can intervene. In the future, it is possible to know exactly what diet and behavioral habits are helping to prolong life and thus help people avoid diseases. In conjunction with the study, the times invited experts to read in detail the health issues that need to be focused on at each of these age points.
Human aging and disease are the overall changes caused by cell damage or death. Back in 1925, well-known american biologist wilson proposed:\" all vital questions of life must be found in cells.\" Niu Wenyi, a professor in the Department of Social Medicine and Health Education at Peking University's School of Public Health, told reporters that although young people are in the stage of being young and relatively mature and stable, the number of cells in the body and the water in the cells are beginning to decrease, which is the first turning point for the body to age. Liu dequan, former director of chinese medicine at the beijing geriatric hospital, said that most of the people around the age of 34 were in a state of heavy family burden, high work pressure and complex interpersonal relationships, which greatly affected physical and mental health.
Experts believe people in their 30s should focus on the health of the nervous system and musculoskeletal muscles. After the age of 30, the blood circulation of the brain slows down, the blood flow decreases, and the number of nerve cells in the brain gradually decreases, thus affecting memory, coordination and brain function. The body's muscle mass peaked at 25 to 30 years of age, and then gradually decreased with age, and then affected the metabolic rate, about 35 years of age, bone loss began. At the age of 30, the heart's ventricular walls and valves will gradually thicken, and the heart's conduction system will begin to age. Meanwhile, lung capacity is beginning to slow down. Yang Ping, secretary-general of the Geriatric Psychology Branch of the Chinese Geriatrics and Geriatrics Society, told reporters that people around the age of 34 are prone to psychological problems such as anxiety and depression due to increased stress and increased sense of responsibility.
Liu Dequan reminds that with the change of people's lifestyle and eating habits, some elderly chronic diseases, such as hypertension, diabetes, arteriosclerosis and so on, more and more occur in the young and middle-aged people, at the same time, the state of long-term fatigue also increases their risk of chronic fatigue syndrome, obesity.
Mr liu said this age group should focus on circulation, digestion and the immune system. Around 60 years of age, the cardiac output per stroke (refers to one heart beat, one side of the ventricular ejection volume) is 30% to 40% less than 20 years of age, the heart conduction system continues to aging, easy to lead to insufficient blood supply and compensatory disorders and other problems. Digestive aspect, about 60 years old, oral cavity, esophagus, gastrointestinal function gradually decline, pancreas due to lipid infiltration and atrophy of gland cells, resulting in trypsin, lipase and other digestive enzyme secretion and decreased activity, digestive function decreased, gastrointestinal disease risk increased. The aging of endocrine system is mainly reflected in the levels of various hormones and the sensitivity of target organs to it. A 10-year study published in the journal Aging shows that the total number of T lymphocytes in the human body decreases with age, and the immune function decreases, making it more vulnerable to bacteria and viruses.
Psychologically, people around the age of 60 are prone to psychological differences and accelerated aging due to a gradual decline in physical function and changes in social functions caused by retirement. Yang also mentioned that more than half of people over the age of 60 have concerns and insecurity about their own health, thus increasing their psychological burden, and more likely to lead to emotional instability, anxiety, depression and other psychological problems.
Around the age of 78, the body's various functions have entered a rapid aging stage, nerve, urinary, respiratory, circulation and other systems, as well as cognitive and psychological changes.
In the nervous system, the number of brain cells and synaptic connections in the elderly decreased, and the blood flow of the brain decreased, resulting in memory loss, fatigue, slow response to external problems. Urinary system, renal arteriosclerosis, renal blood flow decreased, will lead to renal dysfunction. Elderly men are often accompanied by prostatic hyperplasia, frequent urination, urinal urgency, urine sensation; elderly women due to pelvic floor sphincter relaxation, more will appear urinary incontinence symptoms. respiratory system, the elderly will have respiratory muscle strength decline, trachea calcification and other problems, resulting in increased airway resistance, lung ventilation and pulmonary ventilation dysfunction. As the cilia motility weakens, the ability of the elderly to discharge sputum gradually decreases. circulatory system, the 78-year-old people around the thickening of the ventricular wall, peripheral arteriosclerosis, more likely to cause organ ischemia.
This stage of the elderly brain function decline, cognitive degeneration is very obvious. In 2018, a study presented at the annual meeting of the American Population Society showed that brain aging had a partial cognitive impairment period of about four years from the age of 73, and that Alzheimer's or similar cognitive impairment could occur within a year and a half to two years thereafter. On the psychological level, the elderly often show self-centered, conservative, paranoid, impatient, inferiority complex and other psychological problems such as empty nest syndrome.
Although aging is an irreversible process, we can try to delay its progress. Yang Ping said that facing up to aging is the key to delaying aging, and it is especially important to maintain an optimistic attitude, people should get rid of the fear of aging and irritable, lonely depression and other bad emotions in time.
Experts agree that it is important to maintain a good lifestyle and eating habits regardless of age. Should pay attention to balanced diet, diverse structure, mainly cereals, eat more fruits and vegetables, milk, soybeans, eat fish, poultry, eggs, lean meat, less salt and less oil. Lifestyle, pay attention to the combination of work and rest, timely relief of stress, quit smoking and alcohol limit and ensure adequate sleep, pay attention to eat balance, maintain a healthy weight.
Sticking to moderate exercise has a positive effect on delaying aging. It should be noted that the physical quality of the elderly is fully reduced, exercise must be gradual, should choose sports time is not too long, the intensity of the whole body sports activities, such as walking, fast walking, Taijiquan and so on. In addition, no matter which crowd must insist on regular physical examination.
Finally, Liu Dequan reminded that the family's care for the physical and mental health of the elderly has a very positive effect on their health and longevity. In the face of people in their 60s, family members should help them arrange their retirement, encourage them to develop positive interests and hobbies, and make sure that they are old and happy. Most people around the age of 78 will have children away from the empty nest feeling, plus they will often pay too much attention to their own health, the family should be more concerned about care and communication with them at this time. (Reporter: Jiang Yue)
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